TET1 deficiency amplifies macrophage inflammatory signaling associated with Crohn's disease.

Inflamm Res · 2026 · PMC13031220 · PMID 41896302

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showed a trendno p-value reported

Though not statistically significant in these data, TET1 showed a trend toward downregulation in the tissue resident myeloid cells, while CCL8 was found to be significantly increased in the bulk-RNA seq analysis, and trending towards upregulation in the myeloid compartment.

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