Mendelian randomization implicates circulating plasma proteins in gout risk and identifies candidate therapeutic targets.

Int J Immunopathol Pharmacol · 2026 · PMC13031745 · PMID 41885234

Europe PMC DOI

hedged sentence

0.1380

closest p · 2.8× alpha

0.1380

boldest claim

The sentences

did not reach statistical significancep = 0.138not close (p > 0.1)

SPOCK2 exhibited a concordant direction across datasets but did not reach statistical significance (OR = 0.97; 95% CI, 0.92–1.01; p = 0.138; Figure 4 ).

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