Comparative Efficacy of Metabolic/Bariatric Surgery Versus GLP-1 Receptor Agonists: A Network Meta-Analysis of Randomized Controlled Trials.

Obesity (Silver Spring) · 2026 · PMC13032060 · PMID 41326176

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hedged sentence

0.1050

closest p · 2.1× alpha

0.1050

boldest claim

The sentences

did not reach statistical significancep = 0.105not close (p > 0.1)

In subgroup analyses, the comparison of MBS versus semaglutide 2.4 mg showed an ETD of −9.80% (95% CI: −14.63% to −4.97%; p = 0.001), while tirzepatide versus MBS did not reach statistical significance (ETD: −4.79%; 95% CI: −10.81% to 1.22%; p = 0.105).

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