Free water in white matter links focal hemodynamic compromise to cognitive impairment in asymptomatic extracranial carotid artery stenosis.

BMC Med Imaging · 2026 · PMC13032369 · PMID 41721288

Europe PMC DOI

hedged sentences

0.0470

closest p · 0.9× alpha

0.0850

boldest claim

The sentences

borderline significantp = 0.047actually significant

At the ipsilateral level, in the model using PLD 1500ms, ipsilateral FW-WM showed a significant positive association with WMH volume (β = 0.403, p = 0.012) and a borderline significant negative association with LI-CBF-ACA-GM (β = -0.319, p = 0.047).

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showed a trendp = 0.085so close (0.05 < p ≤ 0.1)

Better MoCA scores showed a trend toward correlation with higher LI-CBF-ACA-GM at PLD 1500ms ( r = 0.287, p = 0.085).

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