A randomized double-blind placebo-controlled trial of topical atorvastatin 1% gel in patients with breast cancer undergoing radiotherapy demonstrated significant reductions in radiation-induced breast edema, pruritus, and pain, while the reduction in erythema did not reach statistical significance [ 148 ].
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Radiotherapy-Induced Skin Fibrosis: Pathophysiology, Emerging Therapeutics, and the Role of Dermatology.
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