Patients receiving lower fluid volumes (<0.15 mL/kg/min) had lower overall complication (19% vs 25%) and leak rates (3.2% vs 6.2%); however, these differences did not reach statistical significance, indicating a possible trend toward benefit [ 33 ].
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The Impact of Preoperative Nutritional Status on the Incidence of Anastomotic Leaks in Colorectal Surgery.
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The only statistically significant association observed was an increased risk of line-related complications, whereas trends toward higher reoperation rates and ALs in the TPN group did not reach statistical significance [ 28 ].