Surgical Approach and Microbiologic Trends in Hip Periprosthetic Joint Infection: A Retrospective Comparison of Anterior and Posterior THA.

J Am Acad Orthop Surg Glob Res Rev · 2026 · PMC13034937 · PMID 41945752

Europe PMC DOI

hedged sentences

0.4440

closest p · 8.9× alpha

0.4440

boldest claim

The sentences

did not reach statistical significanceP = 0.444not close (p > 0.1)

Although none of the polymicrobial infections in the anterior cohort involved gram-negative organisms, the difference in gram-negative involvement between anterior and posterior approaches did not reach statistical significance (0 vs. 62.5%, P = 0.444), likely due to the limited number of polymicrobial cases.

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a notable trendno p-value reported

16 , 17 Gram-positive bacteria accounted for most infections in both groups; however, we observed a notable trend toward higher gram-negative infection rates in anterior THA PJIs (18.2 vs. 4.9%), which approached but did not reach statistical significance ( P = 0.076).

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