Association between craniosynostosis and phospholipid metabolism: Insights from single-cell and transcriptomic analysis.

Medicine (Baltimore) · 2026 · PMC13034944 · PMID 41894269

Europe PMC DOI

hedged sentence

0.5300

closest p · 10.6× alpha

0.5300

boldest claim

The sentences

did not reach statistical significanceP = .53not close (p > 0.1)

While this association did not reach statistical significance ( P = .53) likely due to the limited sample size of the craniosynostosis cohort (N = 405), the effect estimate suggests a potential risk reduction, which aligns with the protective role of lipid modulation observed in our VLDL analysis.

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