Barely Significant
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Eptinezumab With Patient Education for Chronic Migraine and Medication-Overuse Headache: The Randomized, Placebo-Controlled RESOLUTION Trial.

Neurology · 2026 · PMC13035099 · PMID 41886713

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Only if an end point demonstrated a statistically significant effect would the formal testing continue to the next end point; this was continued until an end point failed to reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.