Natural History of Psychological Symptoms in Individuals With Rome IV Irritable Bowel Syndrome and Association With Gastrointestinal Symptom Severity.

Abnormal HADS‐anxiety scores at both baseline and 12 months were more likely in those with moderate to severe IBS symptoms at both baseline and 12‐month follow‐up (147 (46.2%) of 318 individuals), although this did not reach statistical significance ( p = 0.019 for trend) (Figure 2 ). 3.2.

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