did not reach statistical significancep = 0.3108
CDKN2A and E2F1 expression was also upregulated in the SOX2 HI quartile relative to SOX2 LOW (not shown, p < 0.0001), while expression differences between SOX2 HI and LOW quartiles for TGFB1 and CDKN1C did not reach statistical significance (not shown, p = 0.3108 and p = 0.1723, respectively).