Utilization of Apixaban Pharmacokinetics for Dose Optimization in High-Risk Elderly Patients.

Clin Pharmacokinet · 2026 · PMC13038646 · PMID 41689732

Europe PMC DOI

hedged sentence

0.3900

closest p · 7.8× alpha

0.3900

boldest claim

The sentences

did not reach statistical significancep = 0.390not close (p > 0.1)

Use of CYP3A4 inducers was associated with a higher likelihood of subtherapeutic concentrations (adjOR 3.5, 95% CI 0.2–64.5) but did not reach statistical significance ( p = 0.390), possibly owing to the small number of patients receiving inducing drugs.

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