Barely Significant
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Effectiveness of fissure sealants following different silver fluoride application protocols in MIH-affected molars: randomized clinical study.

Clin Oral Investig · 2026 · PMC13038748 · PMID 41915094

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Although the difference did not reach statistical significance, no loss of retention was detected at the 12-month follow-up in groups treated with resin-based fissure sealants, whereas each group receiving glass ionomer sealants exhibited retention loss in at least two teeth.

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a decreasing trendno p-value reported
Both indices showed a decreasing trend over time, indicating reduced plaque accumulation and improved gingival health around the treated teeth.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.