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The effect of preoperative tizanidine on postoperative pain and trismus following surgical removal of mandibular third molar: A randomized clinical trial.

SAGE Open Med · 2026 · PMC13039632 · PMID 41929642

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Both groups experienced a decrease in pain scores over time, though the differences in Days 3 and 7 did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.