Barely Significant
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A genetic study of immunity in depression and interactions with childhood maltreatment.

Transl Psychiatry · 2026 · PMC13039853 · PMID 41856978

Europe PMCDOI
1
hedged sentence
0.0590
closest p · 1.2× alpha
0.0590
boldest claim

The sentences

nearly significantp = 0.059so close (0.05 < p ≤ 0.1)
nominal associations in 110 of the studied genes, and nearly significant differences in the polygenic scores for ICD 10-defined depression, p = 0.059, as well as for self-harm behavior, p = 0.073) between individuals within the depression cohort (i.e. moderate to severe depression, with hospitalization) and those with lifetime depression in the population-based cohort (i.e. milder forms of depression, without hospitalization).

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