Brain-wide induction of ΔFOSB and altered co-activation networks in a rat model for exercise training.

Transl Psychiatry · 2026 · PMC13040081 · PMID 41888111

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In addition, running showed a trend towards increased ΔFOSB-positive cell numbers in the prelimbic cortex (PrL), cingulate cortex 2 (Cg2), ventral polymorph layer of the dentate gyrus (vPoDG), basomedial amygdala (BMA), BLA, lateral hypothalamus (LHA) and piriform cortex (Pir) compared to sedentary controls ( P < 0.10; Fig. 3a, b ; Supplementary Table 1 ).

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