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Lactic Acid Drives ESM1 to Attenuate DNA Damage and CD8+ T Cell Infiltration in Cancer.

Oncol Res · 2026 · PMC13040346 · PMID 41930148

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Although CD8+ T cell infiltration levels in HCC and LUAD patients did not reach statistical significance between high- and low-ESM1 groups, the average infiltration in low-ESM1 patients remained higher than in high-ESM1 cohorts ( Fig. 5B – E ). 4.

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