Decreased Severity of Oral Immunotherapy Induced Gastrointestinal Eosinophilic Reactions Following Revisions in Milk-Treatment Protocol.

Allergy · 2026 · PMC13040637 · PMID 41263053

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showed a trendp = 0.06so close (0.05 < p ≤ 0.1)

In the analysis of severe OITIGER in the full cohort, the revised protocol was associated with a significantly lower hazard ratio, consistent with both reduced and delayed risk (HR 0.44; 95% CI: 0.22–0.88; p = 0.02) (Figure 2B ), and AEC > 600/μL showed a trend toward increased risk (HR 1.76; 95% CI: 0.97–3.19; p = 0.06).

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