Oncolytic adenovirus type 11-induced ferroptosis of esophageal squamous cell carcinoma cells involves in mitochondrial impairment and the mTOR pathway.

BMC Cancer · 2026 · PMC13040906 · PMID 41735873

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did not reach statistical significanceno p-value reported

The combination treatments (HAdV-11 + CCI-779 or HAdV-11 + mTOR siRNA) exhibited a further numerical decline in GPX4 relative to HAdV-11 treatment alone, but these additional reductions did not reach statistical significance.

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