Effects of CYP1A2 genetic polymorphisms on the pharmacokinetics of pentoxifylline and its active metabolites.

BMC Pharmacol Toxicol · 2026 · PMC13041349 · PMID 41749399

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

did not reach statistical significanceno p-value reported

Notably, while pentoxifylline exposure was significantly lower in -163 C/A heterozygotes than in -163 C/C individuals, the reduction in -163 A/A homozygotes did not reach statistical significance.

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.