S3RL: Enhancing Spatial Single-Cell Transcriptomics With Separable Representation Learning.

Adv Sci (Weinh) · 2026 · PMC13042551 · PMID 41556263

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a clear trendno p-value reported

While raw data showed weak and inconsistent distance‐related differences, S3RL‐reconstructed data revealed a clear trend of higher Gna14 expression in plaque‐distal regions ( > 40 μ m ), with robust statistical significance and reduced variance.

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