Immune Modulatory Oxysterols Produced from Cholesterol-Containing Lipid Nanoparticles Regulate Tumor Growth.

Although LNP-7-KC did not show a statistically significant difference in tumor growth compared to vehicle-treated mice, LNP-5β,6β-EC showed a trend suggesting enhancement of tumor growth ( Figure A and B) and was associated with a significantly increased tumor K i -67 index ( Figure D and F), indicating enhanced tumor cell proliferation.

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