Barely Significant
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Impact of Sequential Ramucirumab Plus Docetaxel After PD-1 Inhibitors on Anti-PD-1 Antibody-Bound T-Cell Dynamics and Clinical Outcomes.

Cancer Sci · 2026 · PMC13045383 · PMID 41618119

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showed a trendp = 0.05actually significant
Within IgG4 + CD8 + T‐cell subsets, Temra showed a trend toward longer PFS in the high versus low groups (6.2 vs. 4.5 months, p = 0.05) and was significantly associated with longer OS (NR vs. 8.2 months, p = 0.006; Figure 3 ).

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