Topical Airway Lidocaine Spray Reduces the 95% Effective Dose of Sufentanil for Blunting Hemodynamic Response to Tracheal Intubation in Elderly Patients: A Biased-Coin Up-and-Down Sequential Allocation Trial.

Drug Des Devel Ther · 2026 · PMC13048068 · PMID 41939434

Europe PMC DOI

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did not reach statistical significanceno p-value reported

While the difference between the lidocaine and control groups did not reach statistical significance, the trend toward higher incidence in the control group aligns with the expected physiology.

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