Impact of trastuzumab deruxtecan (T-DXd) and brain stereotactic radiosurgery on intracranial control and radionecrosis risk in HER2-positive or -low breast cancer brain metastases.

Breast · 2026 · PMC13049524 · PMID 41875806

Europe PMC DOI

hedged sentence

0.0680

closest p · 1.4× alpha

0.0680

boldest claim

The sentences

showed a trendp = 0.068so close (0.05 < p ≤ 0.1)

Other factors, including age, subtype, and SRS characteristics, did not show statistically significant associations, although estrogen receptor (ER) positivity showed a trend toward increased risk ( p = 0.068).

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.