Testosterone Exposure During Fetal Masculinization Programming Window Determines the Kidney Size in Adult Mice.

At E18.5, a lower portion of AKT was phosphorylated in Hsd17b3 −/− kidneys compared to WT, although the difference did not reach statistical significance due to high variation in WT samples (Figure 5C ). mTORC1 activation leads to phosphorylation of ribosomal protein S6, and thus we analyzed phosphoS6 from fetal kidneys.

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