Metastasis-Associated Wound Repair Promotes Reciprocal Lung Epithelium Activation and Breast Cancer Metastatic Outgrowth.

Although the data did not reach statistical significance, there is a trend toward reduced metastatic proliferation in ROF-treated lungs with little to no change in cell death ( Fig. 6H ; Supplementary Fig.

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Very few differences in cytokine levels were observed when comparing whole lungs with a low versus high metastatic burden, though there was an overall trend in lower cytokine levels with increasing metastatic burden (Supplementary Fig.

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