Barely Significant
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Creatinine-to-albumin ratio for early ICU-course (first 24 hours) risk stratification of mortality in critically ill patients with gastrointestinal bleeding: A retrospective cohort study.

Sci Prog · 2026 · PMC13051087 · PMID 41934121

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a significant trendno p-value reported
After full adjustment (Model 3), the gradient persisted (Q2 HR 1.45, p = 0.113; Q3 HR 2.16, p < 0.001; Q4 HR 2.76, p < 0.001), with a significant trend across quartiles (p for trend < 0.001). 365-day mortality risk Continuous CAR Per-unit increments in CAR were linked to a 24–63% increased risk of mortality (Model 1: HR 1.63, 95% CI 1.44–1.85; Model 2: HR 1.57, 95% CI 1.38–1.79; Model 3: HR 1.24, 95% CI 1.07–1.43; all p ≤ 0.004).

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