The relationship between alcohol use disorder, measures of cognitive decline, and Alzheimer disease biomarkers in middle aged and older adults.

The proportion of Aβ42/Aβ40 values meeting thresholds indicative of elevated amyloid was higher in those with moderate‐to‐severe AUD (64% for <65, 79% for ≥65) compared to those with no AUD (57% for <65, 58% for ≥65) and mild AUD (62% for <65, 74% for ≥65), but this did not reach statistical significance.

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