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RASA2 deletion rescues immune synapse dysfunction, enhancing CAR T cell efficacy against DMGs.

J Immunother Cancer · 2026 · PMC13052770 · PMID 41912267

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RASA2 ablation in CAR T-cells resulted in a slight upward trend in binding strength against SJ-DIPGX7c but did not reach statistical significance ( figure 4E,F ).

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