Calorie Restriction Modulates Gene Expression of Il19 and Il24 during Renal Aging.

Ann Geriatr Med Res · 2026 · PMC13054573 · PMID 41328619

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did not reach statistical significanceno p-value reported

Notably, some cell cycle-related genes, including p15 INK4B , p16 INK4A , and p21 , exhibited consistent directional patterns of age-associated upregulation and CR-associated downregulation, while p15 INK4B and p16 INK4A did not reach statistical significance ( Fig. 2C ).

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