Connectivity in ALS II (CoALS II): a study of structural and functional connectivity in ALS.

Front Neurol · 2026 · PMC13056628 · PMID 41959630

Europe PMC DOI

hedged sentences

0.0650

closest p · 1.3× alpha

0.0650

boldest claim

The sentences

showed a trendp = 0.065so close (0.05 < p ≤ 0.1)

Notably, ALS patients showed a trend toward increased assortativity in resting-state fMRI ( p = 0.065), possibly reflecting altered hub organization. 3.8.

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highly significantno p-value reported

Robust white matter–functional correspondence: diffusion-derived structural connectivity demonstrated strong and highly significant correlations with functional networks across all conditions.

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