Efficacy and safety of different anti-VEGF agents combined with pars plana vitrectomy in proliferative diabetic retinopathy: a systematic review and network meta-analysis of randomized controlled trials.

Front Endocrinol (Lausanne) · 2026 · PMC13056647 · PMID 41958881

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a positive trendno p-value reported

(3) Regarding postoperative visual acuity improvement, all drugs exhibited a positive trend, with conbercept showing the highest degree of improvement.

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did not reach statistical significanceno p-value reported

For some outcomes, such as changes in BCVA, which did not reach statistical significance, further high-quality studies are needed to confirm these findings.

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