Seasonal changes in lipid profiles and homocysteine in patients with and without coronary heart disease: a real-world paired retrospective study in a cold-climate region.

Front Cardiovasc Med · 2026 · PMC13057428 · PMID 41958463

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highly significantno p-value reported

For TG, non-CHD individuals showed a tendency toward lower levels in winter, whereas CHD patients exhibited a slight winter increase, resulting in a highly significant between-group difference in Δ.

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did not reach statistical significanceno p-value reported

Hcy displayed a distinct pattern: a larger winter decrease in Non-CHD but not in CHD, although between-group Δ did not reach statistical significance.

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