Dual-chamber pacing for vasovagal syncope: A systematic review and meta-analysis of randomized controlled trials.

2 ) All trials showed a favorable trend toward reduced syncope recurrence in the active pacing group, with the exception of a single study.

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The test for interaction between these subgroups did not reach statistical significance (p for interaction = 0.39), indicating that although the within-subgroup effect in patients with documented asystole was statistically significant, formal evidence of effect modification was not demonstrated.

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