Association of influenza viral genetic information with severity markers in patients hospitalised with influenza: multicentre retrospective cohort study.

BMJ Open · 2026 · PMC13059944 · PMID 41506775

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showed a trendno p-value reported

Among A(H3N2), the (3C.2a1b.2a.)2b clade showed a trend toward increased severity using the 4-variable definition compared with the 2a.1b clade (aOR 2.9, 95% CI 0.8 to 10.0).

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