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Plasma extrachromosomal circular DNA as a biomarker in EGFR-targeted therapy of non-small cell lung cancer.

Mol Oncol · 2026 · PMC13060643 · PMID 41165514

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We observed a numerically longer PFS and OS for patients with a decreased level of eccDNA compared to those with an increased level of eccDNA, but they did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.