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Multi-omics profiling implicates gut microbiota-sphingolipid interplay in the neuroprotective effects of semaglutide on diabetic cognitive impairment.

Front Microbiol · 2026 · PMC13061865 · PMID 41971325

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a strong trendno p-value reported
It significantly reduced the levels of psychosine and showed a strong trend toward normalizing D-glucosylsphingosine ( Figures 4E–G ).

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