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Incidence of acute exacerbation and its related factors among chronic obstructive pulmonary disease patients aged 40 years and older in China.

Chin Med J Pulm Crit Care Med · 2026 · PMC13063265 · PMID 41970202

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33 Although the association between tobacco exposure and AECOPD incidence did not reach statistical significance in the present multivariable analysis, patients with a history of smoking and higher smoking intensity nonetheless exhibited higher rates of AECOPD.

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