The In Vitro Transgenic Rodent Assay in Primary MutaMouse Hepatocytes Compared to the Mammalian Cell Gene Mutation Assay Using the HPRT Gene.

Environ Mol Mutagen · 2026 · PMC13063353 · PMID 41159280

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a significant trendno p-value reported

Both assays showed a concentration‐dependent increase in cytotoxicity and a statistically significant increase in mutant frequency, with a significant trend in the data.

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