Barely Significant
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BRAF<sup>V600E</sup> patient derived colon cancer organoids identify biomarkers of response to EGFR and BRAF inhibition and replicate clinical data.

J Exp Clin Cancer Res · 2026 · PMC13063721 · PMID 41882736

1
hedged sentence
0.0750
closest p · 1.5× alpha
0.0750
boldest claim

The sentences

showed a trendP = 0.075so close (0.05 < p ≤ 0.1)
Resistant models showed a trend towards enrichment with neuroendocrine cells ( P = 0.075), a significant depletion with enteric neuron cells ( P = 0.04) and a trend towards lower levels of enterocytes and paneth cells ( P = 0.078 and 0.4, respectively) as compared to sensitive models (Suppl.

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