Secretory products from regulatory macrophages modulate senescence in human endothelial cells: implications for cardiovascular aging and diseases.

BMC Cardiovasc Disord · 2026 · PMC13063746 · PMID 41917842

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

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boldest claim

The sentences

did not reach statistical significanceP > 0.05actually significant

Although the number of CD105 positive HUVEC ep and HUVEC lp tended to increase upon addition of SP Mreg , the differences did not reach statistical significance (HUVEC ep + Co: 39.55 ± 11.49%; P > 0.05 vs.

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a slight trendno p-value reported

Regarding the endothelial senescence marker CD105, no statistically significant differences were observed in either HUVEC ep or HUVEC lp following SP Mreg treatment, although there was a slight trend towards increased CD105 positivity in both cell types.

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