Unraveling the oncogenic and immunomodulatory roles of GINS1: a systematic pan-cancer study.

Cancer Cell Int · 2026 · PMC13063887 · PMID 41776634

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showed a trendno p-value reported

Conversely, in patients receiving anti-PD-L1 (Atezolizumab) or anti-CTLA-4 (Ipilimumab) therapies, high GINS1 expression showed a trend toward improved survival (Fig. 8 D-F).

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an increasing trendno p-value reported

The results indicated that GINS1 exhibited an increasing trend with tumor progression across most cancer types, suggesting that GINS1 might serve as a potential biomarker for tumor staging and play a crucial role in cancer invasiveness and metastatic potential.

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