Barely Significant
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Efficacy of nivolumab plus relatlimab versus BRAF/MEK inhibitors for first-line treatment of BRAF-mutant advanced melanoma: A matching-adjusted indirect comparison.

BMJ Oncol · 2025 · PMC13064201 · PMID 41971757

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showed a trendno p-value reported
35 They found that, compared with NIVO+RELA, NIVO+IPI had similar PFS and ORR, while BRAF/MEK inhibitors had similar PFS and significantly higher ORR; NIVO+RELA also showed a trend of fewer grade ≥3 AEs than NIVO+IPI.

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