Barely Significant
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Serum and urinary soluble CD163 in children with active lupus nephritis.

Pediatr Rheumatol Online J · 2026 · PMC13064335 · PMID 41877151

2
hedged sentences
0.0001
closest p · 0.0× alpha
0.0001
boldest claim

The sentences

highly significantP < 0.0001actually significant
The median serum sCD163 in SLE patients was 12.3 ng/mL (IQR: 7.5–20.0), compared with 3.2 ng/mL (IQR: 3.0–3.8) in Non-SLE CKD patients, a difference that was highly significant ( P < 0.0001).

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Additionally, in the current study, despite the significant positive correlation between urine sCD163 levels and SLEDAI scores in SLE patients (groups 1 and 2), the positive correlation between serum sCD163 and SLEDAI scores did not reach statistical significance, this finding can be explained by the inclusion of many factors other than kidney parameters in the SLEDAI grading criteria.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.