Ropivacaine-based Regional Anesthesia Exerts Muscle-protective Effects Despite Elevated Compartment Pressure in a Porcine Model of Acute Compartment Syndrome.

Although the overall median plasma creatine kinase (p-CK) levels were higher in the RPVC group than in the placebo group—for example, at T1, p-CK was 1,687 U/l (IQR, 1,167 to 3,301) in RPVC versus 1,273 U/l (IQR, 893 to 1,378) in placebo, and at T10, p-CK was 1,940 U/l (IQR, 868 to 3,334) in RPVC compared to 1,171 U/l (IQR, 1,020 to 1,467) in placebo—these differences did not reach statistical significance ( P > 0.05; fig. 3 D).

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