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Heterogeneity and immune microenvironment of early invasive estrogen receptor-positive breast cancer reveal an immune-rich subset.

NPJ Breast Cancer · 2026 · PMC13065787 · PMID 41771905

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showed a trendno p-value reported
Notably, pathways related to immune activity, such as myeloid leukocyte migration, leukocyte chemotaxis, type II interferon production and signaling, showed a trend towards negative enrichment scores, indicating upregulation in ERα-low tumours.

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