The I-Learn Cognition and Behavior program for non-pharmacological treatment of agitation in nursing home residents with neurocognitive disorders: A cluster randomized trial.

Alzheimers Dement (N Y) · 2026 · PMC13067200 · PMID 41970152

Europe PMC DOI

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0.2400

closest p · 4.8× alpha

0.2400

boldest claim

The sentences

did not reach statistical significanceP = 0.24not close (p > 0.1)

While a higher proportion of participants in the intervention group also experienced antipsychotic withdrawal, this difference did not reach statistical significance (OR = 3.7, 95% CI: 0.4–32.5, P = 0.24).

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a trend toward significanceno p-value reported

Specifically, we observed a three‐fold increase in the withdrawal of psychotropic medications in the intervention group compared to the control group, with statistically significant effects observed for anxiolytics and a trend toward significance for antidepressants.

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