Although the difference between R6/1 and R6/1:TgRBFOX1 mice did not reach statistical significance, the significant deficits respect to wild type mice found in R6/1 mice, were no longer observed in R6/1:TgRBFOX1 mice (Fig. 3 B).
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Modest rescue of RBFOX1 splicing function attenuates Huntington's disease features.
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