Integrin-Binding Matricellular Protein Fibulin-5 Maintains Epidermal Stem Cell Heterogeneity During Skin Aging.

Fbln5 Deficiency Compromises ECM Integrity at the Epidermal–Dermal Junction in Aging Skin Among the ECM proteins at the epidermal–dermal junction (Fujiwara 2024 ), the RNA‐seq data showed a trend of decreased expression for integrins, collagens, and laminins in the 12‐month‐old Fbln5 KO mice (Figure 3A,B ; Table S5 ).

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